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Lesions of primary and secondary syphilis contain activated cytolytic T cells
W C van Voorhis1, L K Barrett, J M Nasio
1Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, 98195, USA.
Infection and Immunity
|March 1, 1996
Abstract:
This study demonstrates that CD8+ cytotoxic lymphocytes (CTL) are found in both primary and secondary syphilis lesions. CD8+ T cells were detected by immunohistology, and mRNAs for granzyme B and perforin were detected by reverse transcription and PCR, suggesting that CD8+ cytotoxic lymphocytes are activated.