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Confluent and reticulated papillomatosis: response to minocycline
A D Montemarano1, M Hengge, P Sau
1Department of Dermatology, Walter Reed Army Medical Center, Washington, DC 20307, USA.
Background:
Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed.
Objective:
We attempted to evaluate the effectiveness of oral minocycline.
Methods:
Nine patients with CRP were treated with oral minocycline, 50 mg twice a day, for 6 weeks. The average follow-up period was 11 months. Recurrence rate, side effects, and effectiveness of therapy were assessed.
Results:
All patients except two had a 90% to 100% response to therapy. Recurrences were noted in three patients, all of whom responded to re-treatment with minocycline. None of the nine patients had an adverse reaction.
Conclusion:
Minocycline, 50 mg twice a day, is safe and effective for CRP.