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The noncoding and surface envelope coding sequences of myeloblastosis-associated virus are respectively responsible
1Laboratoire d'Oncologie Virale et Moléculaire, Centre National de la Recherche Scientifique-UMR 146, Institut Curie, Centre Universitaire, Orsay, France.
Journal of Virology
|April 1, 1996
Abstract:
The use of chimeric viruses allowed us to establish that myeloblastosis-associated virus long terminal repeat sequences are necessary and sufficient for induction of nephroblastoma in chickens and that the blastemal hyperplasia induced by env SU is not a prerequisite for tumor development but rather constitutes a predisposing stage.