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[Chloroquine poisoning]

S O Semb1, D Jacobsen

  • 1Akuttmedisinsk avdeling, Medisinsk klinikk, Ullevål sykehus, Oslo.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|February 10, 1996
PubMed
Summary
This summary is machine-generated.

Acute chloroquine poisoning is a life-threatening emergency. This case highlights successful treatment of a severe overdose using mechanical ventilation and diazepam, emphasizing prompt medical intervention for this dangerous drug toxicity.

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Area of Science:

  • Pharmacology
  • Toxicology
  • Emergency Medicine

Background:

  • Increased global travel and malaria prevalence have led to wider chloroquine use for prophylaxis and treatment.
  • Acute chloroquine poisoning presents a significant risk of mortality due to cardiac arrest, arrhythmia, and apnea within hours of ingestion.
  • Rapid absorption and high toxicity of chloroquine contribute to sudden, severe clinical manifestations following overdose.