Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

465
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
465
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

741
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
741
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

769
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
769
Long-term Depression01:05

Long-term Depression

33.2K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.2K
Long-term Depression01:03

Long-term Depression

3.2K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.2K
Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

39.8K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
39.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pain catastrophizing and employment histories.

Occupational medicine (Oxford, England)·2014
Same author

The role of religion in psychiatric education: a national survey.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry·2014
Same author

Psychiatry residents' attitudes toward personal involvement in research.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry·2014
Same author

The relationship between borderline personality symptoms and body mass index in a consecutive sample of cardiac stress test patients.

Eating and weight disorders : EWD·2012
Same author

Hair-pulling and borderline personality symptomatology among internal medicine outpatients.

Internal medicine journal·2012
Same author

Mental health history and disruptive behaviours in the medical setting.

Internal medicine journal·2012

Related Experiment Video

Updated: Jan 26, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.3K

Dysthymic disorder: the chronic depression

R A Sansone1, L A Sansone

  • 1University of Oklahoma College of Medicine, Tulsa, USA.

American Family Physician
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

Dysthymic disorder, a chronic mild to moderate depression, is often underdiagnosed. Treatment involves antidepressants like SSRIs, but psychotherapy and support are also key for managing this persistent mood disorder.

More Related Videos

Animal Models of Depression - Chronic Despair Model CDM
05:47

Animal Models of Depression - Chronic Despair Model CDM

Published on: September 23, 2021

8.1K
Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

25.5K

Related Experiment Videos

Last Updated: Jan 26, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.3K
Animal Models of Depression - Chronic Despair Model CDM
05:47

Animal Models of Depression - Chronic Despair Model CDM

Published on: September 23, 2021

8.1K
Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

25.5K

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Dysthymic disorder is a chronic, mild to moderate depression lasting at least two years.
  • It is underdiagnosed, affecting 5-15% of primary care patients.
  • Comorbid conditions and chronic stressors complicate diagnosis and treatment.

Purpose of the Study:

  • To review the diagnostic challenges and treatment options for dysthymic disorder.
  • To highlight the role of comorbid conditions in treatment decisions.
  • To assess the efficacy and limitations of antidepressant therapies.

Main Methods:

  • Literature review of studies on dysthymic disorder.
  • Analysis of diagnostic criteria and treatment guidelines.
  • Evaluation of antidepressant efficacy and patient-reported outcomes.

Main Results:

  • Selective serotonin reuptake inhibitors (SSRIs) are preferred over tricyclic antidepressants for dysthymia.
  • Patients may experience partial remission, oversensitivity to medication, or relapse.
  • Treatment efficacy can be influenced by comorbid conditions.

Conclusions:

  • Dysthymic disorder requires careful diagnosis and management.
  • Pharmacological treatment with SSRIs is moderately effective.
  • Adjunctive psychotherapies and support are crucial for comprehensive care.