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2-Diazopyrroles: synthesis and antileukemic activity
G Cirrincione1, A M Almerico, P Diana
1Istituto Farmacochimico, Università di Palermo, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|April 1, 1996
Abstract:
The title compounds were synthesised in preparative yields by diazotization of the corresponding 2-aminopyrroles. In preliminary screening tests as antileukemic agents they showed modest activity against the murine and human leukemic cell lines FLC and K562S and their multidrug-resistant daunorubicin selected sublines.