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Updated: Aug 14, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
[Clinico-histological scale for identifying preinvasive lesions of the larynx]
C A Alvarez Marcos1, J A Martínez Sánchez, J Noval Menéndez
1Servicio de ORL, Hospital Valle del Nalón. Riaño-Langreo, Asturias.
Abstract:
Preinvasive laryngeal lesions progress to infiltrating carcinoma in 7-15% of cases. Clinical manifestations and histological findings are not reliably predictive of progression. Quantitative cytometry improves predictive effectiveness, but is not a routine procedure. A clinico-histological scale consisting of 13 variables which were combined and used prospectively had a predictive value of 0.8 sensitivity and 0.9 specificity for progression of preinvasive laryngeal lesions.
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