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[The L-arginine/nitric oxide metabolic pathway. Its physiopathology and clinical implications]
G Mengozzi1, F Veglio, D Schiavone
1Dipartimento di Medicina e Oncologia Sperimentale, Università degli Studi di Torino.
Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna
|January 1, 1996
Abstract:
The L-arginine/nitric oxide (NO) pathway plays a key role in a number of biological processes within most organs and systems. Increasing attention has been addressed to its involvement in the pathogenesis of various human diseases. In this review we examine the enzymology of different NO-synthase isoforms, the major NO detection techniques as well as the possible clinical and pharmacological implications of this new metabolic pathway.