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Mandibular invasion by squamous cell carcinoma: a computed tomographic and histological study
T A Huntley1, I Busmanis, P Desmond
1Royal Melbourne Hospital, Melbourne, Australia.
The British Journal of Oral & Maxillofacial Surgery
|February 1, 1996
Summary
Oral cell carcinoma (SCC) primarily enters the mandible through the alveolar crest. Computed tomography (CT) aids in identifying bone involvement, crucial for surgical planning in edentate patients.
Area of Science:
- Oral oncology
- Surgical pathology
- Medical imaging
Background:
- Understanding the spread of oral cell carcinoma (SCC) into the mandible is critical for effective surgical planning.
- Previous knowledge on the precise pathways of SCC invasion into mandibular bone was limited.
Purpose of the Study:
- To investigate the patterns of entry and spread of oral cell carcinoma (SCC) into the mandible.
- To evaluate the utility of computed tomography (CT) in identifying mandibular bone involvement by SCC.
Main Methods:
- Radiographic (CT) and histological examination of 14 resection specimens of mandibular bone and adjacent SCC.
- Correlation of CT findings with histological slices, particularly in edentate cases.
Main Results:
- Eight of 14 specimens showed mandibular bone involvement by SCC.
- The primary site of tumor entry into the bone was consistently the alveolar crest.
- CT demonstrated good correlation with histological findings in identifying bone invasion, especially in edentate cases.
Conclusions:
- The alveolar crest is the main entry point for SCC into the mandible.
- CT is a valuable tool for detecting mandibular bone invasion in edentate patients.
- Findings can inform surgical strategies to maximize bone preservation while ensuring complete tumor excision.