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Preoperative disseminated intravascular coagulation (DIC) associated with aortic aneurysm--does it need to be
1Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Insights
Disseminated intravascular coagulation (DIC) in aortic aneurysm patients often resolves post-surgery. Surgeons should proceed with aortic aneurysm repair even if DIC persists after two weeks of treatment.
Area of Science:
- Vascular Surgery
- Hematology
Background:
- Disseminated intravascular coagulation (DIC) is a known complication of aortic aneurysms.
- Preoperative management of DIC in these patients is critical.
Observation:
- Four patients with aortic aneurysms and preoperative DIC were studied.
- DIC resolved postoperatively in all four cases.
- Preoperative DIC correction was unsuccessful in two patients.
Findings:
- Surgery for aortic aneurysms can effectively resolve DIC, even if persistent preoperatively.
- Intensive preoperative DIC treatment may not always be successful or necessary.
- Delayed surgical intervention is warranted if DIC does not resolve within two weeks of treatment.
Implications:
- Surgical intervention for aortic aneurysms should be prioritized, even with persistent DIC.
- Reconsideration of aggressive preoperative DIC management is suggested.
- Accurate diagnosis of DIC etiology, excluding other pathologies, is essential.
Abstract:
Disseminated intravascular coagulation (DIC) is one of the complications accompanying aortic aneurysm. We herein report four patients with aortic aneurysm who had DIC preoperatively. In all four cases, DIC was corrected immediately after surgery; however, in two cases, DIC could not be corrected preoperatively. This prompted us to reconsider the importance of correcting DIC before surgery. Of the four cases reported in this paper, DIC existed even at the time of surgery in two cases, in spite of meticulous treatment with heparin and/or protease inhibitor; however, the DIC could be removed postoperatively even in these two cases. Surgeons should not waste time with intensive DIC treatment preoperatively. If the DIC cannot be corrected within more than 2 weeks of meticulous treatment, surgeons should then perform surgery on the patient. In addition, it is also essential to ensure that the DIC is due to the aneurysm itself and that no other disease processes have been overlooked.
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