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Coincidental cases of primary sclerosing cholangitis and biliary atresia in siblings?
K Isoyama1, K Yamada, K Ishikawa
1Department of Paediatrics, Showa University Fujigaoka Hospital, Yokohama, Japan.
Acta Paediatrica (Oslo, Norway : 1992)
|December 1, 1995
Abstract:
Familial cases of primary sclerosing cholangitis or biliary atresia have been reported, although genetic influences and immunopathological abnormalities in these diseases are considered to be obscure. We report a case of primary sclerosing cholangitis and biliary atresia in siblings with the observation of HLA-DR antigen expression in the abnormal bile duct epithelial cells.