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-Glucose, insulin and C-peptide kinetics during tocolysis with oral fenoterol-
H H Günter1, A Nitschmann, H J Balks
1Zentrum Frauenheilkunde, Medizinischen Hochschule Hannover, Deutschland.
Objective:
The effect of oral fenoterol therapy (40 mg/day) on the kinetics of glucose, insulin and C-peptide during an oral glucose tolerance test (oGTT; 100 g glucose) was investigated in the third trimester.
Methods:
54 patients without tocolytic therapy (25 with a pathologic oGTT) were compared with 36 patients who received tocolytic therapy (18 patients with a pathologic oGTT).
Results:
The patients with a normal or pathologic oGTT and with or without tocolytic therapy showed no significant differences in respect of the concentrations of glucose, insulin and C-peptide. During tocolytic therapy, an early increase in insulin was observed as well as slightly elevated C-peptide concentrations and a decreased C-peptide/insulin quotient.