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New variant Ph translocation in chronic myeloid leukemia: t(Y;22)(p11;q11)

M S Gallego1, E M Baialardo, M Gutierrez

  • 1Laboratorio de Citogenética, Servicio de Genética, Hospital de Pediatriá, "Juan P Garrahan," Buenos Aires, Argentina.

Cancer Genetics and Cytogenetics
|March 1, 1996
PubMed

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...