Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nuclear pattern recognition by two-parameter texture analysis

G Diaz1, C Cappai, M D Setzu

  • 1Department of Cytomorphology, University of Cagliari, Italy.

Computer Methods and Programs in Biomedicine
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cisplatin-gemcitabine-durvalumab reintroduction in advanced biliary tract cancer: a multinational real-world analysis.

ESMO open·2026
Same author

Baseline neutrophil-to-eosinophil ratio and neutrophil-to-lymphocyte ratio as prognostic markers in patients with unresectable biliary tract cancer treated with gemcitabine-cisplatin-durvalumab: an international, multicentre, retrospective cohort study.

ESMO gastrointestinal oncology·2026
Same author

Lower specificity of mycorrhizal associations in the invader Nicotiana glauca could mediate adaptive advantages over the native plant species during the drought season.

The Science of the total environment·2025
Same author

Elevated CO₂ enhances mycorrhizal inoculation efficiency in phytostabilization of a heavy metal-contaminated soil using Nicotiana glauca.

The Science of the total environment·2025
Same author

Antimicrobial pressure in healthy breeding dogs vs household animals assessed through the resistance profile of Escherichia coli and coagulase positive Staphylococci.

Veterinary journal (London, England : 1997)·2025
Same author

Successful clinical management of canine intestinal lipogranulomatous lymphangitis through exclusive medical and nutritional treatment: four cases (2018-2023).

The Journal of small animal practice·2024
Same journal

SynTME: A tumor microenvironment-aware, pharmacology-inspired multi-stage framework for drug synergy prediction.

Computer methods and programs in biomedicine·2026
Same journal

MMFVS-Net: A triple-symmetric cross-attention network for multimodal optical image fusion and high-accuracy virtual staining of breast cancer tissues.

Computer methods and programs in biomedicine·2026
Same journal

A novel Milstein-stochastic epidemiologically-informed neural network for approaching epidemic dynamics: Application to Mpox disease.

Computer methods and programs in biomedicine·2026
Same journal

Accounting for approximation errors using surrogate-based parameter estimation of cardiac mechanics digital twins.

Computer methods and programs in biomedicine·2026
Same journal

Facial iPPG heatmap patterns based on period-aware autoencoder show association with carotid atherosclerosis towards non-contact hemodynamic assessment.

Computer methods and programs in biomedicine·2026
Same journal

Explainable machine learning models predict liver fibrosis risk and outcome in the general population: Development and multi-cohort external validation.

Computer methods and programs in biomedicine·2026
See all related articles

This study introduces a simple method for analyzing chromatin texture in digitized nuclei images. The technique quantifies chromatin patterns, enabling the identification of distinct nuclear textures for biological research.

Area of Science:

  • Cell Biology
  • Microscopy
  • Image Analysis

Background:

  • Chromatin texture analysis is crucial for understanding nuclear function and cellular states.
  • Existing methods may lack robustness to variations in staining and illumination.
  • Objective quantification of chromatin patterns is needed for reliable biological interpretation.

Purpose of the Study:

  • To develop a simple and robust procedure for analyzing chromatin texture.
  • To identify distinct chromatin patterns in neuronal populations.
  • To provide pure descriptors of nuclear texture independent of densitometry and morphometry.

Main Methods:

  • Standardization of high-resolution digitized nuclear images to invariant gray values.
  • Subdivision of nuclei into grid quadrats (0.4 x 0.4 microns2).

Related Experiment Videos

  • Estimation of gray value standard deviations within quadrats and calculation of overall mean and standard deviation of these values.

    • Main Results:

    • The developed method yields pure descriptors of nuclear texture.
    • At least seven distinct chromatin patterns were identified in a mixed population of developing and degenerating neurons.
    • Results were visually verified by mapping images to bivariate plot points.

    Conclusions:

    • The proposed procedure offers a simple yet effective method for chromatin texture analysis.
    • The derived texture descriptors can differentiate various chromatin states in neurons.
    • This approach provides a valuable tool for quantitative cytology and cell biology research.