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Response of Mycobacterium smegmatis to acid stress
L M O'Brien1, S V Gordon, I S Roberts
1Department of Microbiology and Immunology, University of Leicester, UK.
FEMS Microbiology Letters
|May 15, 1996
Abstract:
Evidence was sought for the existence of an inducible acid tolerance response in Mycobacterium smegmatis. Exposure of M. smegmatis to a sub-lethal, adaptive acidic pH was found to confer a significant level of protection against subsequent exposure to a lethal pH, compared to unadapted cells. Adaptation was dependent on de novo protein synthesis.