[Genetic analysis of differences in alkaline phosphatase activity in two Drosophila virilis strains differing in heat...

Genetic control of changes in alkaline phosphatase activity was studied in adult individuals from two strains of Drosophila virilis under normal conditions and at a high temperature (38 degrees C). Flies from strain 101 responded to the heat shock with a reduction in enzyme activity, whereas flies from strain 147 lacked this response. Strains 101 and 147 were shown to differ in alkaline phosphatase activity at a normal temperature. Genetic analysis of these differences was performed. They were shown to be controlled monogenically (or by a battery of tightly linked genes). The gene determining alkaline phosphatase activity was localized on an autosome.