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Olfactory receptor-encoding genes and pseudogenes are expressed in humans
M L Crowe1, B N Perry, I F Connerton
1Protein Engineering Department, Institute of Food Research, Reading, UK.
Gene
|March 9, 1996
Abstract:
A putative olfactory receptor-encoding gene was cloned from human genomic DNA and shown to be expressed by isolation of a full-length cDNA from olfactory tissue. A second cDNA clone was found to encode an olfactory receptor pseudogene. The expression of a pseudogene from the olfactory gene repertoire, in neurons which express only a single receptor type, implies that many neurons will be non-functional.