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Updated: Aug 14, 2026

A Rapid, Scalable Method for the Isolation, Functional Study, and Analysis of Cell-derived Extracellular Matrix
09:40

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Published on: January 4, 2017

[Biochemical changes in extracellular matrix components of the amniotic sac during its premature rupture]

T Rechberger1, K Postawski, H Donica

  • 1II Kliniki Ginekologii Operacyjnej AM w Lublinie.

Ginekologia Polska
|March 1, 1996
PubMed

In the fetal membranes that have ruptured 12 hours before onset of the labour the tissue collagen content was lower than in control accompanying by similar local collagenase and elastase activity. These results excluded the inflammatory process as the main cause of prelabour preterm rupture of membranes (PPROM). The analysis of the collagen fractions taken from the site of rupture and the location close to umbilical cord indicates that in PPROM there are changes in posttranslational collagen molecule modification.

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