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Use of intravenous dofetilide in atrial flutter with hemodynamic instability
1First Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.
Japanese Circulation Journal
|January 1, 1996
Abstract:
Paroxysmal atrial flutter is a drug-resistant supraventricular tachyarrhythmia that is often accompanied by hemodynamic instability due to an excessive ventricular response. We report here a case of atrial flutter with 1:1 atrioventricular conduction, in which we were able to rescue the patient from a state of cardiogenic shock by using intravenous dofetilide, a new class III antiarrhythmic agent. Dofetilide was suitable for the treatment because it immediately increased atrioventricular nodal refractoriness without any negative inotropic action.