[The combination of chronic calculous cholecystitis and diabetes mellitus]

A total of 206 patients with chronic calculous cholecystitis (CCC) are subjected to operation in the surgical clinic of the Military Hospital--Plovdiv over the period 1991-1994 = Diabetes mellitus as a concomitant disease is discovered in 21 cases (10.20 per cent). All of them have pain syndrome complaints, and during cholecystectomy concrements in the gallbladder are found. As shown by the results, the combination CCC and DM leads to aggravation of the disease. Destructive changes in the gallbladder in this combination are detected in 28.5 per cent, whereas in patients free of DM they amount to 10.5 per cent. Presumably, removal of the gallbladder contributes to eliminate the persisting stress factor in terms of the insular apparatus of the pancreas. Assessment of the long-term results shows that the positive therapeutic effect of the operation is permanent.