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Related Experiment Videos

Cutaneous metastases from prostatic carcinoma

E Piqué Duran1, A Paradela, M C Fariña

  • 1Department of Dermatology, Fundación Jiménez Díaz, Madrid, Spain.

Journal of Surgical Oncology
|June 1, 1996
PubMed
Summary

Cutaneous metastasis from prostate cancer is rare. This study details two cases, one typical and one with a morphea-like plaque, confirming prostatic origin with PSA immunohistochemistry.

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Area of Science:

  • Oncology
  • Dermatology
  • Urology

Background:

  • Cutaneous metastasis from prostate cancer is an uncommon clinical presentation.
  • Metastases typically manifest as nodules in the suprapubic region and anterior thighs.

Observation:

  • This report details two cases of cutaneous metastases from prostate carcinoma.
  • One case exhibited classic nodular lesions, while the second presented as a morphea-like plaque on the chest.

Findings:

  • Histopathological examination of the morphea-like plaque revealed neoplastic cells in a folliculotropic pattern.
  • Immunohistochemical analysis using prostatic specific antigen (PSA) confirmed the prostatic origin in both cases.

Implications:

  • These findings expand the known clinical spectrum of cutaneous prostate cancer metastasis.

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  • Highlights the importance of PSA immunohistochemistry in diagnosing unusual presentations of metastatic prostate cancer.