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Updated: Jul 27, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Published on: January 19, 2016

Improved synthesis of a protected 11-oxoestrone

E Stéphan1, R Zen, L Authier

  • 1Laboratoire de Chimie Organométallique, associé au CNRS, ENSCP, Paris, France.

Steroids
|December 1, 1995
PubMed
Summary

This study details an improved synthesis for 11-oxoestrone-3-acetate-17-ethyleneketal, a key intermediate. The enhanced method achieves a 30% overall yield through strategic oxidation and hydroboration-oxidation steps.

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