[An efficacy and tolerance study of transdermal estrogen replacement therapy with the preparation Systen R50 (Cilag)]

Results from the first study, carried out in our country on the therapeutic effects of Systen [correction of System] R50 TTS in women with peri- and postmenopausal symptoms are reported. Eight women with postcastration syndrome and seven women older than 50 years, with an intact uterus and no vaginal symptoms are reported. Eight women with postcastration syndrome and seven women older than 50 years, with an intact uterus and no vaginal bleeding for at least 6 months were treated. Progesterone was prescribed in the non-hysterectomised patients. In all women enrolled in the study the application of the preparation Systen [correction of System] R50 TTS led to a significant improvement of peri- and postmenopausal symptoms without serious side effects.