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[Sensitivity of bacteria of the genus Proteus to antibiotics]
Insights
This study examined Proteus bacteria in children with enterocolitis. Kanamycin, gentamicin, and carbenicillin were most effective for treating this infection.
Area of Science:
- Microbiology
- Pediatrics
- Infectious Diseases
Background:
- Enterocolitis in children can be caused by Proteus bacteria.
- Antibiotic resistance is a growing concern in treating bacterial infections.
- Understanding Proteus susceptibility patterns is crucial for effective therapy.
Purpose of the Study:
- To determine the antibiotic susceptibility profiles of Proteus isolates from pediatric enterocolitis cases.
- To evaluate the clinical efficacy of specific antibiotics in treating Proteus enterocolitis in children.
Main Methods:
- Analysis of 481 Proteus bacterial cultures isolated from children between 1990-1994.
- In vitro susceptibility testing against 10 different antibiotics.
- Clinical efficacy assessment of antibiotic therapy in 388 children.
Main Results:
- Proteus isolates demonstrated the highest susceptibility to kanamycin, gentamicin, and carbenicillin.
- These three antibiotics were found to be the most effective agents in clinical treatment.
- The study provides data on antibiotic resistance patterns during the 1990-1994 period.
Conclusions:
- Kanamycin, gentamicin, and carbenicillin are recommended for treating Proteus enterocolitis in children.
- Regular monitoring of antibiotic susceptibility is essential for optimizing pediatric infectious disease management.
- This research highlights effective antibiotic choices for Proteus infections in pediatric populations.
Abstract:
Antibiotic susceptibility of 481 cultures of the bacteria belonging to the genus Proteus isolated within 1990-1994 from children with enterocolitis was studied. The study included 10 antibiotics. The efficacy of the antibiotic therapy in 388 children with the above disease was estimated. It was shown that the Proteus isolates were most frequently susceptible to kanamycin, gentamicin and carbenicillin. When used clinically in the treatment of children with Proteus enterocolitis, the antibiotics proved to be the most efficient agents.