Related Experiment Video
Updated: Aug 8, 2026

07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Experimental and clinical study of antibiotics administered intravitreally in endophthalmitis]
Antibiotiki I Khimioterapiia = Antibiotics and Chemoterapy [Sic]
|September 1, 1995
Abstract:
The concentrations of gentamicin and cefotaxime (claforan) in the humor of the anterior chamber and vitreous body of the eye were estimated in the study on the pharmacokinetics of the antibiotics in rabbits. The antibiotics were administered intravitreally in single doses. It was shown that the residence time of the antibiotics in the therapeutic concentrations in the eye cavity was 48 hours. Cefotaxime proved to be the most efficient agent in the prevention and treatment of postoperative endophthalmitis.

