Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Depressive symptoms associated with scleroderma

R P Roca1, F M Wigley, B White

  • 1The Bayview Medical Center, and Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Arthritis and Rheumatism
|June 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adolescent cannabinoid type 1 receptor (CB1R) blockade mitigates the effects of adolescent social instability stress (SS) on socially directed behaviour in female rats.

Psychoneuroendocrinology·2026
Same author

Empathic and agentic artificial intelligence in nursing: perspectives on a human-centered framework for cancer care navigation in the United States.

ESMO real world data and digital oncology·2026
Same author

Autophagy is essential for survival and function of polyploid giant cancer cells under therapeutic stress.

Cancer letters·2026
Same author

Demonstration of a mobile optical clock ensemble at sea.

Nature communications·2025
Same author

Relative sensitivity of plastic scintillator: A comparative analysis with 60Co gamma rays, deuterium-deuterium, and deuterium-tritium neutrons.

The Review of scientific instruments·2024
Same author

Depot buprenorphine as an opioid agonist therapy in New South Wales correctional centres: a costing model.

BMC health services research·2022

Depressive symptoms are common in systemic sclerosis (SSc; scleroderma). They are linked more to personality and self-rated disability than to disease severity, highlighting the need for targeted mental health treatment.

Area of Science:

  • Rheumatology
  • Psychiatry
  • Medical Psychology

Background:

  • Systemic sclerosis (SSc), also known as scleroderma, is a chronic autoimmune disease.
  • Depressive symptoms are a significant concern in patients with chronic illnesses, impacting quality of life.

Purpose of the Study:

  • To determine the prevalence of depressive symptoms in patients diagnosed with SSc.
  • To identify factors associated with depressive symptoms in this patient population.

Main Methods:

  • Fifty-four SSc outpatients completed validated questionnaires assessing depression, personality, functional status, and psychosocial adjustment.
  • Clinical assessments and pulmonary function tests were also performed.

Main Results:

Related Experiment Videos

  • Nearly half of SSc patients reported mild depressive symptoms, with 17% experiencing moderate-to-severe symptoms.
  • Depressive symptoms correlated with younger age, digital ulceration, and self-rated functional impairment.
  • Strong associations were found between depression and personality traits, psychosocial adjustment, and social support.

    • Conclusions:

    • Depressive symptoms in SSc are more closely associated with psychological and self-perceived factors than objective medical severity.
    • Recognizing and treating depression as a distinct comorbidity is crucial for managing SSc patients.