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A new analogue of nifurtimox
I Caracelli1, F M Stamato, B Mester
1Instituto de Física e Química de São Carlos, Universidade de São Paulo, Brazil.
Abstract:
1-¿[(5-Nitro-2-furyl)methylene]amino¿-1,2,4-triazole, C7H5N5O3, is a new analogue of nifurtimox with activity against Tripanosoma cruzi. In the crystal structure, the molecule lies on a mirror plane and has an E-sZ conformation along the N = C-C moiety. The molecules are linked through C-H...O and C-H...N interactions.