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Updated: Aug 10, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment
Published on: September 14, 2013
[Several aspects of non-clostridial anaerobic infection in cancer patients]
Abstract:
The specific features of the development and natural history of nonclostridial anaerobic infection (NACI) were studied in 125 cancer patients with various site tumors. It was shown that after surgery for malignant abdominal and genital tumors, NCAI might develop in the late postoperative period despite antibacterial antianaerobic prevention and even long-term antianaerobic therapy. NCAI treated with antianaerobic therapy was found to run long with aggravations and remissions in patients undergone surgery and drug therapy for genital cancer. Radiation therapy is a risk factor for NCAI in patients with malignant genital neoplasms. The risk factors for NCAI in skin cancer patients are tumor ulceration, second infection, and resolution. The most severe problem is likely anaerobic bacteremia in cancer patients. Anaerobic bacteremia appears to be more common than we thought and this issue requires further in-depth study.
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