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Related Experiment Videos

The technique of sentinel node biopsy

C P Karakousis1, A F Velez, J E Spellman

  • 1State University of New York, Buffalo, New York 14209, USA.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|June 1, 1996
PubMed
Summary

Sentinel lymph node biopsy accurately identifies melanoma spread using a modified Morton technique. This method successfully located sentinel nodes in 93% of patients, proving effective without radioactive tracers.

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Area of Science:

  • Oncology
  • Surgical Pathology
  • Dermatology

Background:

  • Sentinel lymph node biopsy (SLNB) is crucial for melanoma staging.
  • Accurate identification of the sentinel node (SN) is vital for prognosis and treatment planning.

Purpose of the Study:

  • To evaluate the efficacy of a modified Morton technique for sentinel node biopsy in patients with localized melanoma.
  • To assess the reproducibility and accuracy of identifying SNs using isosulfan blue dye.

Main Methods:

  • Fifty-five patients with localized melanoma underwent SLNB using a modified Morton technique.
  • Modifications included increased dye volume, site elevation, sharp dissection, and prioritizing stained nodes/lymphatics.

Main Results:

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  • The sentinel node was identified in 93% (51/55) of patients.
  • Identification rates were high across different basins: axilla (92%), groin (93%), and supraclavicular (100%).
  • The sentinel node was positive for melanoma in 24% (12/51) of identified nodes.

    • Conclusions:

    • The modified Morton technique for SLNB is reproducible and highly accurate.
    • This technique effectively identifies sentinel nodes in over 90% of melanoma patients without radiolabeled tracers.