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Effects of endotoxin on lipid metabolism
I Hardardóttir1, C Grunfeld, K R Feingold
1Department of Medicine, University of California San Francisco, USA.
Biochemical Society Transactions
|November 1, 1995
Abstract:
Endotoxin, via cytokines, induces marked changes in lipid metabolism which are now considered part of the acute phase response. The endotoxin induced hyperlipidemia may represent a nonspecific immune response that can decrease the toxicity of a variety of harmful biological and chemical agents and serve to redistribute nutrients to cells important in host defense. The endotoxin induced changes in lipid metabolism may therefore be beneficial.