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Assignment of the human ST2 gene to chromosome 2 at q11.2
S Tominaga1, J Inazawa, S Tsuji
1Department of Biochemistry II, Jichi Medical School, Tochigi, Japan.
Human Genetics
|May 1, 1996
Abstract:
The human St2 locus has been assigned to chromosome 2, using a human ST2 cDNA clone, by a human/rodent somatic cel hybrid mapping panel. The St2 locus has also been mapped to chromosome 2q11.2, using a human ST2 genomic DNA clone, by in situ hybridization. The locus is very tightly linked to the Il-1r1 locus. Together with the structural similarity of ST2 to IL-1RI, these data suggest functional relationships between these two genes.