[Activity of various enzymes of formed elements in the blood plasma during extracorporeal circulation]

The activity of the enzymes whose high activity is observed in blood cells, such as the glutathione metabolic enzymes glutathione reductase, glutathione-S-transferase, glutathione peroxidase in erythrocytes and monoaminooxidase in the platelets, was examined at different perfusion stages in the plasma of 30 patients undergone open heart surgery. The findings suggest that the enzymes release from the blood cells damaged during extracorporeal circulation into the plasma, which may be useful as a test for defining the degree of perfusion-induced damage of blood cells.