Hepatic spiral CT in children: scan delay time-enhancement analysis
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Published on: March 24, 2023
G D Luker1, M J Siegel, D A Bradley
1Malinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd., St. Louis, MO 63110, USA.
Insights
Optimizing spiral CT scans in children requires precise timing. Delaying scanning until after contrast injection significantly enhances liver visibility, improving diagnostic accuracy in pediatric patients.
Area of Science:
- Radiology
- Pediatric Imaging
- Medical Imaging Techniques
Background:
- Hepatic enhancement in spiral CT is crucial for accurate diagnosis in pediatric patients.
- Optimizing contrast timing is essential for maximizing image quality in pediatric liver imaging.
Purpose of the Study:
- To evaluate the impact of varying time delays between contrast administration and spiral CT initiation on hepatic enhancement in children.
- To determine the optimal scanning delay for improved hepatic contrast enhancement in pediatric spiral CT.
Main Methods:
- Forty-five pediatric patients (2-9 years) underwent spiral CT with sequential liver scans.
- Three scanning groups were established based on timing relative to contrast injection: 80%, 100%, and 150% of injection time.
- Hepatic, aortic, and inferior vena caval enhancement were quantified using region-of-interest measurements.
Main Results:
- The 100% injection time group demonstrated significantly greater mean hepatic enhancement (47.0 HU) compared to 80% (41.4 HU) and 150% (40.6 HU) groups (p < 0.05).
- A mean aortocaval difference exceeding 10 HU was consistently observed across all groups.
- Optimal hepatic enhancement was achieved when scanning commenced immediately upon completion of contrast injection.
Conclusions:
- Initiating spiral CT scanning after complete contrast injection significantly enhances hepatic enhancement in pediatric patients.
- This optimized timing protocol can improve the diagnostic quality of hepatic spiral CT examinations in children.
- These findings provide valuable guidance for pediatric radiologists to enhance liver imaging protocols.
Purpose:
To compare the effect of different time delays between contrast administration and the start of spiral CT scanning on hepatic enhancement in children.
Materials And Methods:
Forty-five children (2-9 years old, mean 6 years) with no evidence of hepatic disease were examined with spiral CT. Sequential spiral scans through the entire liver were performed following a uniphasic injection of nonionic contrast medium. In group 1 scanning started at 80 % of the contrast injection time, in group 2 scanning started at 100 % of injection time, and in group 3 scanning started at 150 % of injection time. Mean hepatic, aortic, and inferior vena caval enhancement were determined using regions-of-interest measurements.
Results:
Mean hepatic enhancement was 41.4, 47.0, and 40.6 HU for the 80 %, 100 %, and 150 % injection times, respectively. Enhancement was significantly greater in the 100 % injection time group (p < 0.05). A mean aortocaval difference of greater than 10 HU was present in all examinations.
Conclusion:
Our results suggest that delaying the initiation of spiral CT scanning until the completion of the contrast injection increases hepatic enhancement in children. These data should help to improve the quality of hepatic spiral CT in pediatric patients.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
