[Persistent pulmonary hypertension in newborns]

One of the most critical problems of neonatology persistent pulmonary hypertension in the newborn, is discussed. This syndrome is characterized by increased resistance in pulmonary vessels leading to hypertension in pulmonary arteries and a recurrence of R > L shunting at the ductus arteriosus and foramen ovale. This leads to deep hypoxia and hypoxemia. It is most important to rule out a congenital cyanotic heart defect in the differential diagnosis. The aim of the treatment is to establish normal ventilation and intrapulmonary shunting as well as to control the symptoms leading to pulmonary hypertension that persist over time. The goal preceding treatment should be to determine the initial cause of the persistent pulmonary hypertension.