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[The importance of interleukin 6 (IL-6) in pathogenesis and diagnosis of renal glomerular diseases]
1Klinika Nefrologiczna Instytutu Medycyny Wewnetrznej Akademii Medycznej w Lodzi.
Postepy Higieny I Medycyny Doswiadczalnej
|January 1, 1995
Abstract:
IL-6 synthesized by various types of cells and has multiple biological functions. In the kidney, IL-6 is synthesized by mesangial cells and acts as an autocrine growth factor. IL-6 was demonstrated in the glomerular mesangium and in the urine of patients with proliferative glomerulonephritis, suggesting that it has an important role in the pathogenesis of renal glomerular diseases.