Tuberculosis makes a comeback

Tuberculosis (TB) has plagued mankind for many centuries. In the past, the number of people affected with this potentially deadly disease declined, but there has been a recent dramatic increase in TB incidence. This increase is attributed largely to people who are coinfected with TB and HIV and to the development of resistant strains of Mycobacterium tuberculosis during the last decade. The US social infrastructure also has contributed to a rapid rise in TB cases due to adverse socioeconomic factors and an increase in the number of immigrants and people infected with HIV. This article gives a historical overview of TB; discusses its diagnosis, transmission and prevention modalities; and provides a case study about a TB-infected patient who required emergent surgical intervention.