Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Benign partial epilepsy in infancy

A Okumura1, F Hayakawa, K Kuno

  • 1Department of Paediatrics, Anjo Kosei Hospital, Japan.

Archives of Disease in Childhood
|January 1, 1996
PubMed
Summary

Benign partial epilepsy in infancy (BPEI) is characterized by specific seizure types and normal development. This study found BPEI to be more common than previously reported, with excellent treatment response.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

UK B.1.1.7 variant exhibits increased respiratory replication and shedding in nonhuman primates.

bioRxiv : the preprint server for biology·2021
Same author

An African pygmy hedgehog adenovirus 1 (AhAdV-1) outbreak in an African pygmy hedgehog (<i>Atelerix albiventris</i>) colony in Japan.

Veterinary and animal science·2020
Same author

A rare case of fetal extensive intracranial hemorrhage and whole-cerebral hypoplasia due to latent maternal vitamin K deficiency.

Journal of neonatal-perinatal medicine·2018
Same author

Erratum.

Journal of leukocyte biology·2018
Same author

High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG.

Leukemia·2017
Same author

Predominant area of brain lesions in neonates with herpes simplex encephalitis.

Journal of perinatology : official journal of the California Perinatal Association·2017

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Clinical Neuroscience

Background:

  • Benign partial epilepsy in infancy (BPEI) is a specific epilepsy syndrome.
  • Understanding its occurrence and characteristics is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To investigate the incidence and clinical features of benign partial epilepsy in infancy (BPEI).
  • To evaluate the diagnostic criteria and treatment outcomes for BPEI.

Main Methods:

  • Retrospective evaluation of 75 infants diagnosed with epilepsy within the first two years of life (1987-1993).
  • Inclusion criteria: complex partial seizures (CPS) or secondary generalized seizures (SGS), normal development, normal interictal EEGs, and good treatment response.
  • Detailed analysis of seizure types, family history, age of onset, EEG findings, treatment duration, and developmental outcomes.

Main Results:

  • Twenty-two patients (29.3%) fully met the criteria for BPEI.
  • The average age of seizure onset was 5.9 months.
  • All patients exhibited normal interictal EEGs, normal psychomotor development, and responded well to treatment, with an average seizure persistence of 3.0 months.
  • Eight patients (10.7%) had a positive family history of epilepsy.

Conclusions:

  • Benign partial epilepsy in infancy (BPEI) appears to be more prevalent than previously suggested by earlier studies.
  • The defined criteria for BPEI are consistent with a distinct epilepsy syndrome with a favorable prognosis.
  • Early diagnosis and appropriate treatment lead to excellent outcomes and normal neurodevelopment in affected children.

Related Experiment Videos