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High incidence of urinary tract infection in patients with coeliac disease
1Department of Clinical Immunology, University of Göteborg, Sweden.
Archives of Disease in Childhood
|February 1, 1996
Insights
Children with coeliac disease have a higher risk of urinary tract infections (UTIs). UTIs were most common in children with active, untreated coeliac disease.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Autoimmune Disorders
Background:
- Coeliac disease is an autoimmune disorder triggered by gluten ingestion.
- Urinary tract infections (UTIs) are common bacterial infections in children.
- The relationship between coeliac disease and UTI risk requires further investigation.
Purpose of the Study:
- To investigate the association between coeliac disease and the risk of developing a first-time UTI in children.
- To determine if active, untreated coeliac disease influences UTI occurrence.
Main Methods:
- Retrospective study design.
- Analysis of patient data from children diagnosed with coeliac disease.
- Comparison of UTI incidence in coeliac children versus a general pediatric population.
Main Results:
- Children with coeliac disease exhibited a significantly elevated risk of first-time UTIs compared to the general pediatric population.
- The majority of UTIs in this cohort were linked to active, untreated coeliac disease.
Conclusions:
- Coeliac disease is associated with an increased susceptibility to UTIs in children.
- Prompt diagnosis and management of coeliac disease may reduce the risk of associated UTIs.
Abstract:
The concomitant occurrence of urinary tract infection (UTI) and coeliac disease was studied retrospectively among children with coeliac disease. There was a significantly higher risk of first time UTI in children with coeliac disease than in an unselected population of children. In the majority of cases UTI was associated with untreated, active coeliac disease.