Bone mineral density in Chinese elderly women with hip fracture

In order to examine the status of osteoporosis of the patients with hip fracture, we assessed the bone mineral density (BMD) of the contralateral hip of 81 elderly females with hip fracture and compared those with 77 normal Chinese women. The age of fracture subjects was 73.5 +/- 6.6 years (mean +/- SD), and 69.2 +/- 6.9 years for the controls. All of these fractures were caused by minor trauma, such as falls from a standing position or slipping to the ground. The Norland 2600 dual-photon absorptiometer (DPA) was used to evaluate the BMD in the femoral neck, trochanter, and Ward's triangle areas. The BMD for the fracture subjects was significantly lower than those of the controls. By linear regression, the probability of fracture increased exponentially with age and low BMD. The mean BMD for femoral neck of the fracture subjects versus controls was 0.556 versus 0.624 g/cm2; for trochanter: 0.505 versus 0.566 g/cm2; for Ward's triangle: 0.432 versus 0.485 g/cm2. Both negative predictive value (NPV) and positive predictive value (PPV) were acceptable at the prevalence of hip fracture of 5% or 20% and at a cutoff point of 0.65 g/cm2. These data revealed that the degree of relative osteoporosis in the patients with hip fractures was more severe than that of controls.