Related Experiment Videos
Nutritional support to prevent and treat multiple organ failure
1Ideon Research Center, University of Lund, Suite A 230, Beta House, S-22370 Lund, Sweden.
World Journal of Surgery
|May 1, 1996
Summary
Early enteral nutrition (EN) offers significant benefits over parenteral nutrition for postoperative patients. Jejunal tube feeding and specific nutritional strategies enhance recovery and prevent complications like sepsis.
Area of Science:
- Clinical Nutrition
- Gastroenterology
- Surgical Recovery
Background:
- Enteral nutrition (EN) is preferred over parenteral nutrition (PN) for postoperative/posttrauma patients due to technological advancements enabling early feeding.
- Jejunal tube feeding demonstrates advantages over gastric feeding, including faster metabolic recovery and reduced risks of vomiting and aspiration.
- Early EN supports splanchnic and hepatic circulations, improving mucosal blood flow and preventing intramucosal acidosis and permeability issues.
Purpose of the Study:
- To highlight the advantages of early jejunal enteral nutrition (EN) in postoperative/posttrauma patients.
- To discuss nutritional strategies for enhancing gastrointestinal (GI) health, sepsis prevention, and mucosal integrity.
- To introduce the concept of eco-immune nutrition for optimizing recovery.
Main Methods:
- Review of current technologies and benefits of early enteral nutrition (EN), particularly jejunal feeding.
- Discussion of physiological mechanisms, including nitric oxide (NO) release, saliva's role, and gastric acidity in gut health.
- Recommendations for specific nutritional components: NO-donating substances, nitrate-rich foods, protective lipids, antioxidants, prebiotics, fiber, and probiotics.
Main Results:
- Immediate EN, initiated at 25 ml/hr and advanced to 100 ml/hr, is recommended.
- Emphasis on water purity for immunocompromised patients and avoidance of H2 blockers and saliva-inhibiting drugs.
- Inclusion of prebiotics (>10g fiber/day) and probiotics (e.g., Lactobacillus plantarum 299) supports colonic mucosa and gut flora.
Conclusions:
- Early jejunal EN is crucial for faster recovery, improved gut function, and prevention of complications.
- A comprehensive nutritional approach, including specific micronutrients and pre/probiotics, is vital for mucosal health and sepsis prevention.
- Eco-immune nutrition offers a novel strategy for delivering mucosa-reconditioning ingredients to enhance patient outcomes.