Cytomegalovirus sinusitis. A new manifestation of AIDS

Cytomegalovirus is a common pathogen in patients infected with the human immunodeficiency virus. In this article, cytomegalovirus sinusitis is described and documented for the first time, to our knowledge. Cytomegalovirus was cultured from the sinuses of four patients who were positive for the human immunodeficiency virus and who had antibiotic-resistant infections. In one patient who underwent surgery, cytomegalovirus inclusions were documented consistent with invasive infection. Optimal treatment has yet to be determined, but in this case surgery did provide temporary relief of sinus symptoms.