Related Experiment Videos
Octreotide effects on orthostatic hypotension in patients with multiple system atrophy: a controlled study of acute
R Bordet1, J Benhadjali, A Destée
1Service de Neurologie A, CHU, Centre Hospítalier Universitaire, Lille, France.
Clinical Neuropharmacology
|February 1, 1995
Abstract:
In nine patients with orthostatic hypotension due to multiple system atrophy, the effects of octreotide (100 micrograms s.c.), a somatostatin analogue, on blood pressure (BP), heart rate (HR), and norepinephrine (NE) plasma levels after 60 degrees head up tilt test were evaluated by a randomly controlled study. Octreotide increased supine BP, tilt-test duration (+28%), and delay to obtain minimal BP during the 60 degrees head up tilt (+50%). Octreotide changed neither HR nor NE plasma levels.