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Adult onset Kawasaki disease diagnosed by the echocardiographic demonstration of coronary aneurysms

G Van Camp1, P Deschamps, F Mestrez

  • 1Department of Cardiology, St Pierre University Hospital, Brussels, Belgium.

European Heart Journal
|August 1, 1995

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View abstract on PubMed

Summary
This summary is machine-generated.

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  • Biomedical And Clinical Sciences
  • Paediatrics
  • Infant And Child Health
  • Adult Onset Kawasaki Disease Diagnosed By The Echocardiographic Demonstration Of Coronary Aneurysms

    • This case report details a 17-year-old boy with adult-onset Kawasaki disease, presenting with giant coronary aneurysms and widespread arterial inflammation. The findings highlight that adult Kawasaki disease can be severe and involve multiple arteries.

    Area of Science:

    • Cardiology
    • Rheumatology
    • Pediatrics

    Background:

    • Kawasaki disease (KD) is a pediatric vasculitis primarily affecting coronary arteries.
    • Adult-onset KD is rare, with limited data on its presentation and severity.

    Observation:

    • A 17-year-old male presented with prolonged fever, conjunctivitis, angina, and cervical adenopathy, initially treated with amoxicillin.
    • He developed acute respiratory distress syndrome requiring intubation and renal insufficiency necessitating hemodialysis.
    • Echocardiography revealed giant coronary artery aneurysms, confirmed by angiography, alongside abnormalities in medium-sized arteries.

    Findings:

    • This case represents the first documented instance of adult-onset Kawasaki disease with giant coronary aneurysms.
    • The patient exhibited extensive arterial involvement beyond the coronary arteries, including cerebral, hepatic, mesenteric, and iliac arteries.
    • Laboratory findings were consistent with systemic inflammation and vasculitis.

    Implications:

    • The severe presentation underscores that adult-onset Kawasaki disease can follow a non-benign clinical course.
    • This case expands the understanding of KD manifestations in older individuals.
    • It emphasizes the need for heightened awareness and prompt diagnosis of KD in adolescents and adults presenting with suggestive symptoms.

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