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Cloning of the cDNA encoding the sodium channel beta 1 subunit from rabbit
1Department of Pharmacology Yale University School of Medicine, New Haven CT06520-8066, USA. belcher@biomed.med.yale.edu
Gene
|May 8, 1996
Abstract:
Here, we report the nucleotide (nt) sequence of the cDNA encoding the sodium channel beta 1 subunit from rabbit (o beta 1). Cloning of the o beta 1 cDNA was accomplished by reverse transcription-polymerase chain reaction using rabbit brain RNA as a template for cDNA synthesis. The nt sequence of the o beta 1 cDNA predicts a 218-amino-acid polypeptide which is 96.3 and 97.3% identical to the beta 1 from human (h beta 1) and rat (r beta 1), respectively.