The murine gene encoding apolipoprotein D exhibits a unique expression pattern as compared to other species
Related Experiment Video
Updated: Sep 13, 2026
12:54
Transient Expression of Proteins by Hydrodynamic Gene Delivery in Mice
Published on: May 5, 2014
Gene
|June 1, 1996
Abstract:
The ApoD cDNA coding for murine apolipoprotein D (ApoD) was cloned from a mammary gland library and sequenced. The nucleotide sequence and encoded mature protein are highly homologous to those of rabbit and human. Interestingly, unlike in other species, ApoD RNA is not found in spleen, liver, pancreas or kidney.
Related Concept Videos
02:23RNA Editing
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
02:32Exon Recombination
The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes.
Exon shuffling follows “splice frame rules.” Each exon has three reading...
Exon shuffling follows “splice frame rules.” Each exon has three reading...