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Related Experiment Videos

Radiosensitization of normal tissue by chloroquine

J F Utley, C R Sachatello, Y Maruyama

    Radiology
    |July 1, 1977
    PubMed
    Summary

    Chloroquine, an arthritis drug, may increase radiation sensitivity. Studies show chloroquine combined with radiation therapy led to more severe reactions in both patients and rats, indicating a radiosensitizing effect.

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    Area of Science:

    • Oncology
    • Pharmacology
    • Radiotherapy

    Background:

    • Severe radiation reactions, including chest wall necrosis, can occur after radiotherapy.
    • Chloroquine is a medication used to treat arthritis and other conditions.
    • The potential for drug-induced radiosensitization requires further investigation.