Related Experiment Video
Updated: Aug 19, 2026

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
Published on: June 30, 2018
The effect of modification of acrylic resins on controlled release and bioadhesion
M Vlachou1, N H Choulis, M Efentakis
1Department of Pharmacy, University of Athens, Greece.
Abstract:
The effect of various treatments on the properties of an acrylic matrix was studied, in terms of its swelling properties in buffer solution. The release of two types of drugs from those matrices and their bioadhesive character were also considered. Calcium stearate and sodium lauryl sulfate were used as additives for the matrix treatment. 2-Hydroxyethyl methacrylate was also used as a reactive agent for the acrylic resin treatment. The main function of the above chemicals is the modification of the hydrophilic/hydrophobic character of the matrix. This investigation showed that controlled release systems can be designed by adjusting the matrix properties via additives or chemical reaction.
Related Concept Videos
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
Modified-Release Drug Delivery Systems: Rate-Programmed II
Modified-Release Drug Delivery Systems: Influencing Factors
Modified-Release Drug Delivery Systems: Bioavailability
Modified-Release Drug Delivery Systems: Drug Release Characteristics
Site-Targeted Drug Delivery Systems: Polymeric Carriers

