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Related Experiment Videos

Hydrogen peroxide 3% exposures

M C Henry1, J Wheeler, H C Mofenson

  • 1State University of New York at Stony Brook, USA.

Journal of Toxicology. Clinical Toxicology
|January 1, 1996
PubMed
Summary
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Ingesting hydrogen peroxide 3% is typically harmless, but even small amounts can cause severe stomach and duodenal injury in children. Seek medical attention for persistent vomiting or bloody emesis after exposure.

Area of Science:

  • Toxicology
  • Pediatric Gastroenterology
  • Emergency Medicine

Background:

  • Hydrogen peroxide (H2O2) is a common household antiseptic.
  • Accidental ingestions are frequently reported to poison control centers.

Observation:

  • A retrospective review analyzed 670 hydrogen peroxide 3% exposures over 40 months.
  • Most exposures (77%) were oral, primarily in children (67%), and often asymptomatic (85.6%).

Findings:

  • One child developed gastric ulcers and duodenal erosions after ingesting 2-4 oz of 3% hydrogen peroxide.
  • While most exposures had benign outcomes, severe gastrointestinal injury is possible.

Implications:

  • Healthcare providers should consider gastrointestinal injury in children with persistent vomiting or bloody emesis after H2O2 ingestion.

Related Experiment Videos

  • Endoscopy may be necessary to evaluate for severe gastric injury following significant H2O2 ingestion.