Molecular biology of normal development, malignancy and its suppression

Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.

Cell death and differentiation·2012

Apoptotic signaling by c-MYC.

Oncogene·2008

Leukemia suppressor function of Egr-1 is dependent on transforming oncogene.

Leukemia·2008

Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia.

Oncogene·2007

Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells.

Oncogene·2006

Hematopoietic cells from gadd45a-deficient and gadd45b-deficient mice exhibit impaired stress responses to acute stimulation with cytokines, myeloablation and inflammation.

Oncogene·2006

Inhibition of PINK1/Parkin-mediated mitophagy enhances the susceptibility of breast cancer to cuproptosis.

Oncogene·2026

Functional deficiency of circadian regulator PER2 enhances breast cancer susceptibility and progression with immunosuppression.

Oncogene·2026

Targeting the SELP/PSGL1 axis reprograms M2 macrophages and enhances anti-PD-1 efficacy in gastric cancer.

Oncogene·2026

Clinical metastatic cancer from initiation to colonization: emerging challenges and breakthroughs.

Oncogene·2026

Nuclear amphiregulin and lamin A contribute to genomic stability and the response to replication stress via regulation of heterochromatin.

Oncogene·2026

Complementary intra- and extracellular AGR2 activities support epithelial ovarian cancer cell aggressiveness.

Oncogene·2026

[Effect of ESR1 Somatic Mutations on SERM/SERD Binding: Insights from Molecular Docking and Molecular Dynamics Simulations].

Molekuliarnaia biologiia·2026

RASA2 Promotes Pancreatic Cancer Metastasis by Activating TGFβ-Dependent Non-canonical Hedgehog Signaling.

Cancer research·2026

BRIGHTLINE-1: When a Negative Trial Reveals Two Active Therapies.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026

The pan-tumor landscape, allelic status, and genomic complexity of SMARCA4 alterations.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026

CAR T Cells Targeting an Intracellular Leukemia Antigen Promiscuously Presented by Diverse HLA-II Alleles.

Blood cancer discovery·2026

Impact of GAD-65 Antibody Detection on Antihyperglycemic Therapy in T2D.

Endocrine connections·2026

Related Experiment Videos

Molecular biology of normal development, malignancy and its suppression

Related Concept Videos

Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.

Apoptotic signaling by c-MYC.

Leukemia suppressor function of Egr-1 is dependent on transforming oncogene.

Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia.

Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells.

Hematopoietic cells from gadd45a-deficient and gadd45b-deficient mice exhibit impaired stress responses to acute stimulation with cytokines, myeloablation and inflammation.

Inhibition of PINK1/Parkin-mediated mitophagy enhances the susceptibility of breast cancer to cuproptosis.

Functional deficiency of circadian regulator PER2 enhances breast cancer susceptibility and progression with immunosuppression.

Targeting the SELP/PSGL1 axis reprograms M2 macrophages and enhances anti-PD-1 efficacy in gastric cancer.

Clinical metastatic cancer from initiation to colonization: emerging challenges and breakthroughs.

Nuclear amphiregulin and lamin A contribute to genomic stability and the response to replication stress via regulation of heterochromatin.

Complementary intra- and extracellular AGR2 activities support epithelial ovarian cancer cell aggressiveness.

[Effect of ESR1 Somatic Mutations on SERM/SERD Binding: Insights from Molecular Docking and Molecular Dynamics Simulations].

RASA2 Promotes Pancreatic Cancer Metastasis by Activating TGFβ-Dependent Non-canonical Hedgehog Signaling.

BRIGHTLINE-1: When a Negative Trial Reveals Two Active Therapies.

The pan-tumor landscape, allelic status, and genomic complexity of SMARCA4 alterations.

CAR T Cells Targeting an Intracellular Leukemia Antigen Promiscuously Presented by Diverse HLA-II Alleles.

Impact of GAD-65 Antibody Detection on Antihyperglycemic Therapy in T2D.

Related Experiment Videos

Molecular biology of normal development, malignancy and its suppression

Related Concept Videos

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