Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microvascular thermal equilibration in rat cremaster muscle

L Zhu1, D E Lemons, S Weinbaum

  • 1Department of Mechanical Engineering, City College of The City University of New York, NY 10031, USA.

Annals of Biomedical Engineering
|January 1, 1996
PubMed
Summary

This study measured thermal equilibration in rat cremaster muscle using infrared thermography. Results show blood flow and axial conduction significantly influence heat exchange in microvessels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The tumor suppressor effect of the glucocorticoid receptor in skin is mediated via its effect on follicular epithelial stem cells.

Oncogene·2006
Same author

Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia.

Diabetologia·2006
Same author

Anti-inflammatory effects of inhaled nitric oxide are optimized at lower oxygen concentration in experimental Klebsiella pneumoniae pneumonia.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]·2006
Same author

[Isolation by suppression-subtractive hybridization of genes preferentially expressed during early and late fiber development stages in cotton].

Molekuliarnaia biologiia·2006
Same author

Amelogenins in human developing and mature dental pulp.

Journal of dental research·2006
Same author

Risk assessment of organic pesticides pollution in surface water of Hangzhou.

Environmental monitoring and assessment·2006

Area of Science:

  • Physiology
  • Biophysics
  • Thermodynamics

Background:

  • Understanding thermal equilibration in microvasculature is crucial for tissue physiology.
  • Previous models often neglected axial conduction, limiting accuracy.
  • Direct experimental measurement of thermal equilibration in microvessels is challenging.

Purpose of the Study:

  • To directly measure axial countercurrent thermal equilibration in a microvascular tissue.
  • To develop and validate a theoretical model incorporating axial conduction.
  • To investigate the influence of blood flow and vessel diameter on thermal equilibration.

Main Methods:

  • Utilized high-resolution infrared thermography for detailed surface temperature measurements.
  • Employed an exteriorized rat cremaster muscle preparation.

Related Experiment Videos

  • Administered pharmacological agents to manipulate local blood flow (Peclet number).
  • Modified a theoretical model to include axial conduction and experimental setup parameters.

    • Main Results:

    • Demonstrated that larger arteries (1A) exhibit thermal nonequilibration under normal conditions.
    • Showed surface temperature profiles are sensitive to tissue inlet temperature.
    • Identified critical Peclet number ranges where axial conduction or countercurrent blood flow dominates thermal equilibration.
    • Validated the modified theoretical model against experimental data.

    Conclusions:

    • Axial conduction is dominant at low Peclet numbers (Pe < 1 mm), while countercurrent blood flow dominates at higher Peclet numbers (Pe > 3 mm).
    • The axial equilibration length is proportional to the blood flow Peclet number when countercurrent flow is dominant.
    • The findings provide a more accurate understanding of heat transfer in microvascular networks.